O-161. Postmenopausal ovarian function and endometrial cancer

Ovarian Metastasis in Endometriod Type Endometrial Cancer

Experimental approaches to endometrial and ovarian cancer.

THE most well-known types of hormone-dependent tumours are those of breast, endometrium and prostate, but several other types probably exist (Crowley, 1969; Crowley & Duwe, 1969). Because of their special nature they are open to endocrine manipulation in ways not possible in other tumours. Tumours of the ovary are not easily characterized in this respect as there are so many types and several a...

ovarian metastasis in endometriod type endometrial cancer

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P-161: Effect of Naloxone on Endometrial Growth

Background: There is fine correlation between the infertility and lessening of endometrial thickness. In this study the effects of sedative naloxone, and L-arginine, the precursor of nitric oxide (NO), on endometrial thickness of rat uterus was examined. Materials and Methods: Wistar rats (weighing 200-250 g) in Diestrous phase received intra-peritoneal (i.p.) 1. single L-arginine (50 mg/kg), 2...

Long-term postmenopausal hormone therapy and endometrial cancer.

Estrogen-alone therapy (ET) or estrogen and progestin (EPT) as menopausal hormone therapy (HT) has been commonly used to alleviate menopausal symptoms. Treatments containing > or = 10 days per month of progestin are considered relatively safe with respect to endometrial cancer risk. However, the endometrial safety of long-term EPT regimens is uncertain. We conducted a case-control study of 311 ...